research 688 Precise and efficient editing of the COL7A1 gene in RDEB derived iPSCs with CRISPR/Cas9 and prime editing
CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.
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5 / 1000+ resultsresearch Strategies for High-Efficiency Mutation Using the CRISPR/Cas System
This review discusses strategies to improve CRISPR/Cas systems by addressing limitations like off-target effects and delivery inefficiencies, offering practical guidance and highlighting future applications, but reports no new research findings.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
This review discusses advances in CRISPR/Cas9 variants and nanoformulations for cancer treatment, noting challenges and prospects for clinical application, but reports no new research results.
research Gene Editing Technologies in Aesthetic Dermatology—Mechanisms, Emerging Applications, and Patient Safety Paradigms
This study discusses the transformative potential of gene editing technologies, such as CRISPR-Cas9, for personalized aesthetic interventions in dermatology, but highlights the need for rigorous safety measures, ethical considerations, and careful regulatory oversight before clinical application.
research Non-viral delivery of the CRISPR/Cas system: DNAversusRNAversusRNP
This article reviews CRISPR/Cas system delivery methods for genome editing and highlights RNA's promise in non-viral in vivo applications but reports no new clinical results.
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