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In this study, a bioengineered construct using a biodegradable polycaprolactone mat cocultured with human keratinocyte and rabbit dermal fibroblast cells demonstrated potential as a tissue-engineered skin substitute, showing good cell adhesion and growth.

In this study, researchers found that hair follicles and dermal fibroblasts, including dermal papilla cells, supported sustained hair growth in transplanted murine models, with RNA-seq analysis revealing active signaling pathways and gene expression patterns.

The study introduced an advanced skin model, ImmuSkin-MT, which effectively distinguished between different strengths of skin sensitizers by mimicking the interaction of immune cells in skin tissue.

In this study, researchers developed self-assembled skin models derived from hair follicle cells, offering an ethical and reliable alternative to animal testing and bovine collagen in dermatological research by providing functional dermal and epidermal layers for substance evaluation.

This study found that amplifying Wnt signaling, either genetically or through topical application of liposomal Wnt3a, improved skin wound healing in a mouse model.