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research A Two-Step Culture Method for Efficient Production of Trichogenic Keratinocytes

16 citations, May 2015 in “Tissue Engineering Part C-methods”

A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.

research Alopecia

January 2018 in “Elsevier eBooks”

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

research Alopecia in Harlequin Mutant Mice Is Associated with Reduced AIF Protein Levels and Expression of Retroviral Elements

4 citations, December 2020 in “Mammalian genome”

Harlequin mutant mice have hair loss due to low AIF protein levels and retroviral element activity.

research Establishment of an In Vitro Organoid Model of Dermal Papilla of Human Hair Follicle

44 citations, June 2018 in “Journal of Cellular Physiology”

Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.

research Recreation of a Hair Follicle Regenerative Microenvironment: Successes and Pitfalls

8 citations, May 2021 in “Bioengineering & translational medicine”

Hair growth environment recreated with challenges; stem cells make successful skin organoids.

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Community Join

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community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community HairClone developing cell replacement treatments for Hair Loss

6 upvotes 5 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 489 upvotes 3 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

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