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GlossaryHepatotoxicity

refers to liver damage caused by chemicals or drugs

Hepatotoxicity, also known as liver toxicity, refers to liver damage caused by chemicals, drugs, or natural substances. It can result in a range of liver dysfunctions, from mild enzyme elevations to severe liver failure. This condition is significant in both clinical and pharmacological contexts, as the liver plays a crucial role in metabolizing substances, and its impairment can lead to serious health consequences.

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research Severe Thiopurine-Induced Myelotoxicity and Hair Loss in Japanese Patients with NUDT15 Gene Variant: A Retrospective Case-Control Study

April 2018 in “Journal of Investigative Dermatology”

Screening for the NUDT15 gene variant can prevent severe side effects from thiopurine drugs in East-Asian people.

research PH Sensitive Nano Layered Double Hydroxides Reduce the Hematotoxicity and Enhance the Anticancer Efficacy of Etoposide on Non-Small Cell Lung Cancer

65 citations , October 2015 in “Acta Biomaterialia”

The nano-carrier makes etoposide safer and more effective against lung cancer.

research Tyrosine Kinase Inhibitors Against Cancer: Their Safety in 216 Moroccan Patients

January 2021 in “Journal of Cancer Therapy”

Tyrosine Kinase Inhibitors are effective against cancer but can cause skin, digestive, and blood side effects, including hair loss.

research Efficacy of Albumin-Bound Paclitaxel Combined with Nedaplatin in Neoadjuvant Therapy for Esophageal Squamous Cell Carcinoma: A Single-Center Retrospective Observational Study

1 citations , March 2023 in “Medicine”

The combination therapy is effective and well-tolerated for treating esophageal cancer.

research Adult Group B Streptococcal Disease

13 citations , July 1996 in “Annals of Internal Medicine”

International medical graduates outperformed U.S. graduates on an internal medicine exam.

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community Have to share with you guys. I’m 41. Can’t believe this is actually working. I was bald as hell 1 year ago. I have a ways to go still. Pics of all products included. Most purchased on Amazon

in Progress Pictures 1315 upvotes 1 year ago

A user shared their successful hair regrowth using a combination of derma stamping, Retinol, Minoxidil, Dutasteride, and RU58841, with no side effects. Others discussed their varied experiences with these treatments, including concerns about potential side effects like heart issues and sexual dysfunction.

community Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others.

in Finasteride/Dutasteride 52 upvotes 2 years ago

Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.

community Thoughts about ORAL ketoconazole? (pills)

in Ketoconazole 2 months ago

Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.