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GlossaryBone Marrow Transplantation (Hematopoietic Stem Cell Transplant)

medical procedure replacing damaged bone marrow with healthy stem cells

Bone Marrow Transplantation (BMT), also known as Hematopoietic Stem Cell Transplantation (HSCT), is a medical procedure used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. This treatment is often used for patients with certain cancers like leukemia or lymphoma, as well as other blood or immune system disorders. The healthy stem cells can come from the patient (autologous transplant) or a donor (allogeneic transplant).

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research Six Cases of Permanent Alopecia After Various Conditioning Regimens Commonly Used in Hematopoietic Stem Cell Transplantation

40 citations, September 2007 in “Bone marrow transplantation”

Certain chemotherapy drugs can cause permanent hair loss in stem cell transplant patients.

Rapid Full Engraftment and Successful Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation With Reduced Intensity Conditioning in Omenn Syndrome

research Rapid Full Engraftment and Successful Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation With Reduced Intensity Conditioning in Omenn Syndrome

8 citations, August 2009 in “Pediatric transplantation”

A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.

research Dermatologic Conditions of the Early Post-Transplant Period in Hematopoietic Stem Cell Transplant Recipients

5 citations, October 2018 in “American Journal of Clinical Dermatology”

Skin problems are common after stem cell transplants, and early treatment by dermatologists can improve patient outcomes.

research Permanent Chemotherapy-Induced Alopecia After Hematopoietic Stem Cell Transplantation Treated With Low-Dose Oral Minoxidil

4 citations, February 2022 in “JAAD case reports”

The document concludes that low-dose oral minoxidil successfully regrew hair in a patient with permanent hair loss after chemotherapy and stem cell transplant.

research Categorization of Long-Lasting Hair Changes in Patients After Hematopoietic Stem Cell Transplants

August 2018 in “Journal of the American Academy of Dermatology”

Patients often experience long-lasting changes to their hair after stem cell transplants.

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community Painkillers May Block Minoxidil

in Research/Science 14 upvotes 5 months ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.