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research Mycobacterial 65,000 MW heat-shock protein shares a carboxy-terminal epitope with human epidermal cytokeratin 1/2.

31 citations , October 1992 in “PubMed”

This study demonstrated immunological cross-reactivity between mycobacterial heat-shock protein 65 and human epidermal cytokeratin 1/2, suggesting that this cross-reactive epitope might play a role in skin diseases.

research Expression of the heat shock protein-27 in the adult human scalp skin and hair follicle: Hair cycle–dependent changes

24 citations , April 2006 in “Journal of the American Academy of Dermatology”

This study reported that HSP27 protein shows varied expression in human scalp hair follicles across anagen, catagen, and telogen stages, suggesting a role in hair follicle biology.

research Heat shock protein 25 plays multiple roles during mouse skin development

14 citations , January 2005 in “Cell Stress and Chaperones”

research The Role of Heat Shock Proteins in the Pathogenesis of Polycystic Ovarian Syndrome: A Review of the Literature

3 citations , January 2023 in “International Journal of Molecular Sciences”

This review summarizes current knowledge on the role of heat shock proteins in the pathogenesis of PCOS and their potential implications in developing new treatment strategies, but it reports no new experimental results.

research Single-cell analysis of basal cell carcinoma reveals heat shock proteins promote tumor growth in response to WNT5A-mediated inflammatory signals

1 citations , October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that targeting HSP70 can suppress basal cell carcinoma growth, underscoring the importance of tumor microenvironment interactions in cancer progression.

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Community Join

5 / 146 results

community I tried mixing 3 grams RU58841 into 60ml minoxidil 5% solution and shook for 5 minutes and I can still see tiny crystals floating around like a snow globe when I shine a torch in the bottle

4 upvotes 5 months ago

OP mixed RU58841 with minoxidil and initially saw crystals, but realized they were bubbles. They asked for advice on application frequency for a 5% solution.

community Minoxidil cannot survive summer in warehouses or UPS trucks

64 upvotes 1 month ago

Minoxidil's effectiveness may not be significantly impacted by high temperatures during shipping, as it undergoes stability tests to withstand extreme conditions. Users discuss concerns about oxidation and storage, but experts suggest that short-term exposure to heat is unlikely to degrade the product.

community (Topical) Quercetin might be a good add on to the hair loss stack

8 upvotes 3 years ago

Quercetin might help with hair loss by inhibiting HSP-70, which increases androgen receptors. Concerns include its staining properties and unclear topical absorption.

community Isn't it kind of strange that hair loss happens at where the 2 main superficial temporal arterty branches (temples and crown) are?

5 upvotes 3 years ago

Hair loss may be linked to blood flow and inflammation, with treatments like Minoxidil, finasteride, and quercetin being discussed. The conversation also mentions the role of 5AR enzyme distribution in hair follicles.

community 12 month fin update. Long curly hair

676 upvotes 1 year ago

A user experienced significant hair regrowth after using 1mg of finasteride daily for a year, avoiding minoxidil due to its toxicity to cats. They attributed success to quitting smoking, a better diet, and reduced stress, with only watery semen as a side effect.

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Learn

1 / 801 results

learn capsicum

Can the heat from capsicum actually wake up dormant hair follicles? Capsicum heat may stimulate dormant hair follicles through increased blood flow and growth factors.

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