learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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4 / 4 resultslearn Microneedling
technique to create small wounds in skin to activate collagen production and hair growth
learn Neem Oil
natural substance from Neem tree with medicinal and pesticidal properties
learn Spironolactone
powerful topical and oral anti-androgen used mostly by women
Research
5 / 1000+ resultsresearch Hair Follicle Associated Pluripotent (HAP) Stem Cells from Young Mice Have the Greatest Potential to Differentiate to Cardiac Muscle Cells
Young mice's hair follicle stem cells are best for turning into heart muscle cells.
research Differentiation of Human Dermal Mesenchymal Stem Cells into Cardiomyocytes by Treatment with 5-Azacytidine: Concept for Regenerative Therapy in Myocardial Infarction
Skin stem cells were turned into heart cells using a chemical, suggesting a new way to treat heart attacks.
research Protective Effects of BCC Against Oxidative Stress in Cardiomyocyte Cells
BCC can protect heart cells from damage caused by oxidative stress.
research Rat Hair-Follicle-Associated Pluripotent Stem Cells Can Differentiate Into Atrial or Ventricular Cardiomyocytes in Culture Controlled by Specific Supplementation
Rat hair-follicle stem cells can become heart cells with specific supplements.
research Early-Age-Dependent Selective Decrease of Differentiation Potential of Hair-Follicle-Associated Pluripotent Stem Cells to Beating Cardiac-Muscle Cells
Younger mice's hair-follicle stem cells are better at turning into heart cells than older mice's.
Community Join
5 / 1000+ resultscommunity Hair came back in 3 months at 39y/o.
A user shared their successful hair regrowth using a combination of minoxidil, caffeine, biotin, and RU58841, along with weekly dermarolling. However, others advised against the user's plan to switch to rosemary oil and microneedling only, emphasizing the importance of continuing the current treatment to maintain the results.
community Finasteride is Good for Heart Health!
Finasteride, a hair loss and prostate drug, may also benefit heart health. Some users discuss the potential negative effects of DHT on the heart and the balance between hair loss treatments and heart health.
community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found
The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.
community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year
A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth
PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.