78 citations
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January 2013 in “Brachytherapy” This study found that high-dose-rate electronic brachytherapy was effective for treating nonmelanoma skin cancer, with no recurrences and good to excellent cosmetic results at 1 year or more.
September 2023 in “HAL (Le Centre pour la Communication Scientifique Directe)” In this study, peptide-based nanoparticles were successfully used to deliver the CRISPR-Cas9 system into cancer cells, effectively targeting and editing KRAS mutations, suggesting promising therapeutic potential for cancer treatment.
June 2024 in “International Journal of Nanomedicine” This review outlines recent progress in CRISPR/Cas9 genome editing, discussing its structure, mechanisms, and the use of genetic, chemical, and physical strategies to enhance precision and reduce off-target effects despite some persistent challenges for clinical application.
April 2019 in “Journal of Investigative Dermatology” This study demonstrated that gene-corrected 3D skin constructs from RDEB patient-derived iPSCs, grafted onto immunocompetent mice, showed normal collagen VII expression after two months.
September 2013 in “International journal of radiation oncology, biology, physics” This study found that high dose rate electronic brachytherapy was effective for non-melanoma skin cancer, with no recurrences and good to excellent cosmesis up to three years post-treatment.