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    Did you mean Hand-Foot Skin Reaction?
    GlossaryHand-Foot Syndrome (Hand-Foot Skin Reaction)

    causes redness, swelling, and pain on palms and soles

    Hand-Foot Syndrome, also known as Palmar-Plantar Erythrodysesthesia (PPE), is a side effect of certain chemotherapy drugs. It causes redness, swelling, and pain on the palms of the hands and the soles of the feet, and in severe cases, can lead to blistering and peeling of the skin. This condition occurs because the chemotherapy drugs leak out of the capillaries in these areas, leading to inflammation and damage.

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      Chemotherapy and Cutaneous Drug Reactions

      research Chemotherapy and Cutaneous Drug Reactions

      1 citations, January 2015 in “Springer eBooks”
      Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.
      Skin Toxicity of Anti-Cancer Therapy

      research Skin Toxicity of Anti-Cancer Therapy

      19 citations, October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft”
      Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
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      Cutaneous Toxicities of Cancer Therapy

      research Cutaneous Toxicities of Cancer Therapy

      114 citations, March 2002 in “Current opinion in oncology/Current opinion in oncology, with cancerlit”
      Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.

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