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GlossaryGlabrous Skin (Hairless Skin)

hairless skin on palms, soles, and certain genital areas

Glabrous skin refers to areas of the body that are naturally hairless and smooth, such as the palms of the hands, soles of the feet, and certain parts of the genitalia. This type of skin lacks hair follicles and is typically thicker and more sensitive to touch due to a higher density of nerve endings.

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Production of Ultraviolet-Light-Induced Skin Erythema in the Hairless Rat: A Comparison with the Haired Rat in Screening for Anti-Inflammatory Drugs

research Production of Ultraviolet-Light-Induced Skin Erythema in the Hairless Rat: A Comparison with the Haired Rat in Screening for Anti-Inflammatory Drugs

3 citations, October 1979 in “Laboratory animals”

Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.

research Microimaging of Hairless Rat Skin by Magnetic Resonance at 900 MHz

21 citations, September 2008 in “Magnetic Resonance Imaging”

MRI can effectively image skin structures noninvasively.

research Intragenic Deletion in the Desmoglein 4 Gene Underlies the Skin Phenotype in the Iffa Credo Hairless Rat

28 citations, October 2004 in “Differentiation”

A gene deletion causes the "hairless" trait in Iffa Credo rats.

research Permeation and Distribution of Finasteride Through Hairless Rat Skin: In Vitro Study

1 citations, January 2012 in “42nd Annual Meeting of the European-Society-for-Dermatological-Research (ESDR)”

research Transdermal Permeation of Drugs in Various Animal Species

149 citations, September 2017 in “Pharmaceutics”

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

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community So we’re just ok with taking a research chemical now?

in Treatment 175 upvotes 3 years ago

The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.

community Theory And Observation: Why Being Bald Can Really Work

in Shaved/buzzed 88 upvotes 11 months ago

The original poster believes shaving his head made him more attractive to a specific group of women, despite being less attractive overall. The conversation includes various opinions on attractiveness, with some agreeing that being bald can work for certain men, while others suggest maintaining hair is generally more appealing.

community New BBC article on Finasteride just dropped

in Chat 318 upvotes 1 week ago

Finasteride and minoxidil are discussed as hair loss treatments, with mixed opinions on side effects like sexual dysfunction and mood changes. Some users report positive results, while others express concerns about potential risks and insufficient information.

community Why is Kevin Mann (Haircafe) Hated?

in Chat 62 upvotes 1 year ago

Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

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