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Research

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research Differences in Hair Follicle Dermal Papilla Volume are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses

231 citations , December 1999 in “Journal of Investigative Dermatology”

This study found that the volume of a hair follicle's dermal papilla is strongly correlated with its size, primarily due to the number of cells it contains and the volume of extracellular matrix.

research Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action

37 citations , October 2009 in “Dermatology”

This study suggests that the action of minoxidil in stimulating hair growth likely occurs at the follicular dermal papilla, though it does not induce new follicle formation.

research Development of predictive regression model for perceived hair breakage in Indian consumers

1 citations , March 2019 in “International Journal of Cosmetic Science”

In this study, researchers developed a regression model that reasonably predicts consumer-perceived hair breakage using various parameters such as hair smoothness, detangling forces, extensional strength, and hair density among Indian women.

research Intragenic deletion in the Desmoglein 4 gene underlies the skin phenotype in the Iffa Credo “hairless” rat

28 citations , October 2004 in “Differentiation”

This study identified a large deletion in the desmoglein 4 gene as the genetic basis of the Iffa Credo "hairless" rat's skin phenotype, linking it to lanceolate hair mutations.

research Disulfide Cross-Linked Network Structure of Intermediate Filament and Matrix in Hair and Wool Cortices

4 citations , January 2015 in “Sen'i Gakkaishi”

This study proposed a network model for the cross-linked structure of keratin-associated proteins in hair and wool fibers, suggesting notable differences between the two, potentially affecting hair fiber elasticity.

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Community Join

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community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community GH peptides + KLOW blend saved my hair. before and after pics.

833 upvotes 6 months ago

Using finasteride and peptides, including GHK-Cu, improved hair thickness and regrowth. The user also used a KLOW blend and CJC/IPA for better sleep and recovery.

community Best Ketoconozole shampoo that doesn’t dry out hair?

in Ketoconazole 13 upvotes 1 year ago

People are discussing ketoconazole shampoos that don't dry out hair, with suggestions including using it as a topical treatment, switching to T-Sal, and using moisturizing products like hyaluronic acid serum and biotin conditioner. Regenepure DR is confirmed to still contain ketoconazole, and some users recommend using moisturizing shampoos and conditioners to prevent dryness.

community Dental technician is convinced that he has found the cause of pattern hair loss

314 upvotes 2 years ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community Sandalore experiment

18 upvotes 7 years ago

A user added sandalore to minoxidil for hair loss, observing some vellus hair growth and less scalp inflammation. Others tried sandalore with mixed results, discussing dosage and effectiveness compared to minoxidil and finasteride.

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Learn

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learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.

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Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas