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research Description and characterization of a hair coat disorder in schipperkes

1 citations , December 2018 in “Veterinary dermatology”

This study documented that symmetrical, noninflammatory alopecia in schipperkes is associated with hormonal abnormalities and hair cycle arrest, resembling Alopecia X clinically and histologically.

research Successful deslorelin implant treatment in a neutered female Pomeranian dog with Alopecia X

January 2025 in “Brazilian Journal of Veterinary Medicine/Revista Brasileira de Medicina Veterinária”

This source describes the first successful use of a deslorelin acetate implant to treat alopecia X in a neutered female dog, achieving profuse hair regrowth in 9 months, suggesting an uncomplicated and cost-effective alternative after melatonin failure.

research Abstracts of the 28th Annual Congress of the ECVD‐ESVD, 24–26 September 2015, Krakow, Poland

September 2015 in “Veterinary Dermatology”

This study found that microneedling induced nearly complete hair regrowth in two Pomeranians with alopecia X, suggesting it may be a promising alternative treatment for similar hair cycle arrest disorders.

research Novel insights into the pathways regulating the canine hair cycle and their deregulation in alopecia X

18 citations , October 2017 in “PLOS ONE”

This study found that in Pomeranians with Alopecia X, key genes in the Wnt and Shh signaling pathways and stem cell markers are downregulated, which may explain the absence of anagen hair follicles.

research XMU-MP-1 induces growth arrest in a model human mini-organ and antagonises cell cycle-dependent paclitaxel cytotoxicity

4 citations , September 2020 in “Cell division”

In this study, XMU-MP-1 unexpectedly reduced cell proliferation and altered cell cycle progression in a model human hair follicle, possibly due to off-target kinase inhibition.

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Community Join

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community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community Why do people on this sub die on the hill that fin/dut doesn't give regrowth in most cases?

in Research/Science 121 upvotes 1 year ago

Finasteride and dutasteride mainly stop hair loss, with little regrowth. Minoxidil is better for regrowth, but results differ per person.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community TDM-105795 phase 2 results are in!

27 upvotes 2 years ago

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

community I have tried many treatments but it's getting worse. 23M.

90 upvotes 1 year ago

A 23-year-old male experiencing worsening hair loss has tried topical Minoxidil, Finasteride, Progesterone, Hydrocortisone butyrate, and Ketoconazole. He is considering switching to oral Finasteride due to concerns about side effects and lack of improvement.

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Learn

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learn Hair Transplant

What happens after a hair transplant? Expect mild swelling and redness, with new hair growth starting in 3 to 6 months.
When will I see new hair growth after a hair transplant? New hair growth usually starts 2-4 months after a hair transplant.

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Clinics

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70
Trichology
The Pharmacy for Hair Loss & Scalp Disorders, PLLC.Brentwood, TN · US

Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas