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research Ethanol Extract of Asiasari Radix Preferentially Induces Apoptosis in G361 Human Melanoma Cells by Differential Regulation of p53

2 citations , August 2019 in “BMC Complementary and Alternative Medicine”

Asiasari radix extract may be a potential treatment for melanoma because it selectively triggers cell death in melanoma cells by affecting p53 regulation.

research Sebocytes Are the Key Regulators of Androgen Homeostasis in Human Skin

196 citations , May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology”

Sebocytes play a key role in controlling androgen levels in human skin.

research Fisetin Promotes Hair Growth by Augmenting TERT Expression

22 citations , October 2020 in “Frontiers in Cell and Developmental Biology”

Fisetin, a type of polyphenol, may help hair grow by increasing certain protein activities in cells.

research ALKBH5-Mediated m6A Demethylation Fuels Cutaneous Wound Re-Epithelialization by Enhancing PELI2 mRNA Stability

8 citations , July 2023 in “Inflammation and Regeneration”

ALKBH5 helps wounds heal faster by stabilizing PELI2 mRNA.

research Reduced SMAD2/3 Activation Independently Predicts Increased Depth of Human Cutaneous Squamous Cell Carcinoma

11 citations , February 2018 in “Oncotarget”

Lower SMAD2/3 activation predicts more severe skin cancer.

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community Minoxidil is NOT an Anti-androgen. No.

in Research/Science 43 upvotes 4 weeks ago

Minoxidil is not an anti-androgen; it is a growth stimulator and does not lower DHT like finasteride or dutasteride. Minoxidil can cause side effects like facial swelling and anxiety due to its vasodilator properties.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Minoxidil is a 5ar inhibitor according to research

in Research/Science 148 upvotes 2 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community Wait, so retinol actually helps with hair growth? I heard it was the other way around a while ago and just accepted it..

in Treatment 6 upvotes 6 years ago

Retinol can help with hair growth, contrary to previous beliefs. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Do any of you guys feel like your 20s have been wasted?

in Chat 184 upvotes 1 year ago

A user expressed frustration about hair loss and its impact on their 20s, mentioning financial struggles and mental health concerns. Responses included advice on positive thinking, self-improvement, and seeking treatment options like Minoxidil and finasteride.

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