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      Stem Cell Heterogeneity and Plasticity in Epithelia

      research Stem Cell Heterogeneity and Plasticity in Epithelia

      129 citations, May 2015 in “Cell Stem Cell”
      Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
      Emerging Interactions Between Skin Stem Cells and Their Niches

      research Emerging Interactions Between Skin Stem Cells and Their Niches

      426 citations, August 2014 in “Nature Medicine”
      Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
      Epigenetic Control of Adult Stem Cell Function

      research Epigenetic Control of Adult Stem Cell Function

      179 citations, July 2016 in “Nature Reviews Molecular Cell Biology”
      Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

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