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research MendelVar: gene prioritization at GWAS loci using phenotypic enrichment of Mendelian disease genes

2 citations , April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

This article discusses the MendelVar webserver, which integrates Mendelian disease data with GWAS findings to prioritize candidate genes for complex traits and reports no new experimental results.

Progress on Genome-Wide Association Studies and Selection Signature Analysis for Agronomic Traits in Chinese Sheep and Goats: Review

research Progress on genome-wide association studies and selection signature analysis for agronomic traits in Chinese sheep and goats: review

October 2025 in “Animal Bioscience”

This review summarizes the application of genome wide association studies and selection signature analyses in sheep and goat breeding in China, highlighting genomic regions that influence traits like reproductive performance and body size.

research Molecular Genetics of Alopecias

9 citations , January 2015 in “Current problems in dermatology”

This review highlights recent genetic research advancements in understanding hereditary hair diseases but reports no new study results, emphasizing the identification of genes related to both monogenic and polygenic hair disorders.

research Male-pattern hair loss: Comprehensive identification of the associated genes as a basis for understanding pathophysiology

April 2023 in “Medizinische Genetik”

This review discusses the current status of genetic research on male-pattern hair loss and reports no new findings, outlining significant achievements and future challenges in understanding its biology and treatment.

Cicatricial Alopecia Research Foundation Meeting, May 2016: Progress Towards the Diagnosis, Treatment, and Cure of Primary Cicatricial Alopecias

research Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias

22 citations , January 2018 in “Experimental Dermatology”

This article reviews insights into the pathogenesis of primary cicatricial alopecias, such as lichen planopilaris, provided by emerging technologies, but it does not report new clinical results.

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Community Join

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community Sugar and Hair loss connections

in Research/Science 41 upvotes 1 year ago

High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

community The theory that explains everything. Community Crowdfund

103 upvotes 5 years ago

3aHSD enzyme's role in hair loss and a crowdfund for research. Goal: explore new treatments, study RU58841, and develop natural topical product.

community UPDATE: The theory that explains everything. Please help me make this big!

447 upvotes 5 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

133 upvotes 2 years ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community 3α-Hydroxysteroid dehydrogenase community driven study, not anytime soon guys.

106 upvotes 5 years ago

High cost of studying 3α-Hydroxysteroid dehydrogenase in hair loss led to suggestions of crowdfunding for research. Users discussed using Procyanidin B2/melatonin topical treatment and tracking funds with blockchain.

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Clinics

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52
Hair Loss TreatmentsTrichology
Institute of Trichology StudiesFort Worth, TX · US

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