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research The Gut-Brain-Skin Axis and Role of Intestinal Dysbiosis in Acne Vulgaris: Therapeutic Effects of Pro- and Prebiotic Use

2 citations , January 2018 in “Elsevier eBooks”

This review discusses the complex mechanisms behind acne vulgaris and suggests that dietary modification, along with pro- and prebiotics, may influence its pathogenesis by addressing stress-induced skin inflammation.

research Can gut flora changes be new biomarkers for depression?

1 citations , September 2017 in “Frontiers in Laboratory Medicine”

This review discusses recent research on the relationship between gut microflora and depression, highlighting the potential for new insights into the pathogenesis and treatment of major depressive disorder.

research Gut microbes and skin disease, gut-brain-skin axis: A review

3 citations , January 2017 in “Chinese Science Bulletin (Chinese Version)”

This review discusses the gut-brain-skin axis and its role in skin diseases, advocating for treatments that integrate gut microbiota, mental health, and dietary interventions, but reports no new clinical results.

research Antioxidants and Long Covid

4 citations , January 2022 in “OAlib”

This paper discusses the complex interplay between Long Covid symptoms and various chronic fatigue-related conditions but reports no new clinical findings.

research Psychiatric disorders in women with polycystic ovary syndrome

3 citations , September 2024 in “Journal of Pre-Clinical and Clinical Research”

This study reviews the current understanding of psychiatric disorders in women with PCOS, finding links to the gut-brain axis, neurotransmitter and neuroendocrine dysfunction, and suggests the need for routine mental health screening in these patients.

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Community Join

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community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 44 upvotes 2 years ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community Hair loss research is a money grab

227 upvotes 10 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community Finasteride does deplete important nuero-active steroids

11 upvotes 3 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

community I'm convinced creatine causes hair loss for me

207 upvotes 6 months ago

Creatine is believed by some to cause hair loss, potentially by increasing DHT levels, despite conflicting evidence. Users report mixed results when combining creatine with treatments like finasteride, dutasteride, and minoxidil.

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Experts

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Trichologist
Alison Brain
United Kingdom

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Alison Brain