March 2022 in “Molecules” This study found that adenosine promotes hair growth by stimulating the Wnt/β-catenin pathway in cultured human dermal papilla cells through activation of the adenosine receptor.
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May 2019 in “BMC Complementary and Alternative Medicine” This study found that Bacillus/Trapa japonica fruit ferment filtrate extracts enhanced human hair follicle dermal papilla cell proliferation through the Akt/ERK/GSK-3β signaling pathway, suggesting potential benefits for alopecia treatment.
February 2025 in “Applied Sciences” This study found that extracts from heterotropic cultures of Scenedesmus deserticola JD052 enhanced hair-inductive properties in human dermal papilla cells more effectively than photoautotrophic extracts, likely through activation of AKT/β-catenin signaling, despite similar loliolide content.
This study suggests that melatonin enhances the growth properties of DP cells by activating the AKT/GSK3β/β-catenin signaling pathway through its receptors in a 3D culture system.
This study found that melatonin may enhance hair growth properties in dermal papilla cells by activating the AKT/GSK3β/β-catenin signaling pathway through melatonin receptors.