19 citations
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January 1974 in “Laboratory animals”
In this study, inducing zinc deficiency in recently weaned female Tan rabbits led to reduced food consumption, weight loss, and reproductive issues, including inactive uterine and ovarian changes.
April 2017 in “Journal of Pharmaceutical Investigation”
In this study, the administration of indole-based compounds, particularly L-Tryptophan and Tryptophol, to a PCOS-induced rat model resulted in an increased number of healthy ovarian follicles and a reduction in ovarian cysts compared to untreated rats, suggesting potential therapeutic efficacy.
6 citations
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February 2021 in “Journal of Ovarian Research”
In this study, 150 kHz electromagnetic radiation reduced the number and size of follicular cysts in a rat model of polycystic ovary syndrome without causing significant morphological damage to developing follicles.
2 citations
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August 2022 in “Middle East Fertility Society Journal”
This study found that combining fructose and DHT in rats successfully mimicked the clinical phenotypes of non-lean PCOS, providing a novel rodent model for this condition.
July 2023 in “International Journal of Endocrinology”
In this study, researchers observed that Centratherum anthelminticum seed extract effectively reduced cholesterol, triglycerides, insulin resistance, and inflammatory markers, while normalizing hormone levels and oxidative stress markers in rodents with PCOS, suggesting potential benefits for managing the condition.