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Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function

research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function

31 citations , July 2004 in “Molecular Medicine”

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

research Female Pseudohermaphroditism Caused by a Novel Homozygous Missense Mutation of the GR Gene

94 citations , April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

research Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables

86 citations , December 2001 in “Experimental dermatology”

Mutant mice help researchers understand hair growth and related genetic factors.

High-Resolution Structures of Mutants Affecting Access to the Ligand-Binding Cavity of Human Lipocalin-Type Prostaglandin D Synthase

research High-Resolution Structures of Mutants Affecting Access to the Ligand-Binding Cavity of Human Lipocalin-Type Prostaglandin D Synthase

5 citations , July 2014 in “Acta Crystallographica Section D-biological Crystallography”

Mutations in the enzyme don't significantly change how it binds to its specific substances.

research Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant

8 citations , June 2012 in “PloS one”

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

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community End of Hair loss ( AGA ) ? Since they produce it in china probably we don’t need to wait other 10 yrs😁

in Treatment 271 upvotes 2 weeks ago

GT20029 is a new hair loss treatment in Phase 3 trials in China, using PROTAC technology to target androgen receptors, potentially with fewer side effects than finasteride and minoxidil. VDPHL01, a second-generation minoxidil, is also mentioned as potentially more effective.

community Finally live! alcohol-free, propylene glycol–free topical finasteride foam

in Update 14 upvotes 4 months ago

A new alcohol-free, propylene glycol-free topical finasteride foam is available for prescription in Canada and the USA, offering a cleaner alternative for hair loss treatment. The product also offers a combination of 0.1% finasteride with 5% minoxidil and aims to be affordable and less irritating for sensitive scalps.

community Anyone know a supplier for 3in1 (Min+Fin+Biotin) medication in Europe?

in Treatment 1 upvotes 6 months ago

A user is seeking a European supplier for a 3-in-1 hair loss medication containing Minoxidil, Finasteride, and Biotin. Suggestions include using forwarding services and a UK-based provider, with discussions on potential import taxes.

community Lab results from actifolic RU58841

in Product 39 upvotes 2 years ago

The post discusses the user's experience with hair loss treatment RU58841, which was tested for quality and found to be 96+% pure. The conversation includes various responses, with some users questioning the safety of the product and others expressing satisfaction with the test results.

community I’ve been using min and nizoral for 7 years, losing a lot of hair in the meantime. Here’s what happened when I added 1mg fin daily and 1.5mm micro needling weekly.

in Progress Pictures 212 upvotes 3 years ago

The positive effects of Finasteride, a hair loss treatment; and various other treatments such as Minoxidil and Nizoral that can be used to treat hair loss. Additionally, other methods are discussed, such as micro needling and taking spearmint supplements, which have been seen to help in some cases.

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