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This review discusses the causes and treatment options for idiopathic hirsutism and reports that various therapies may reduce hirsutism severity and the Ferriman–Gallwey score by 35–40% after one year.

In this case study, researchers observed a 5.8-year-old male with peripheral precocious puberty due to a germ cell tumor, marked by elevated human chorionic gonadotropin levels. Treatment normalized hormone levels and arrested the puberty progression, highlighting melatonin's potential role in transitions to central precocious puberty.

This study reported that treatment with gonadotropin-releasing hormone analogs and cross-sex hormones appears appropriate for carefully selected youth with gender dysphoria, but long-term safety needs further investigation.

This review discusses the therapeutic options for transgender individuals, including hormonal and surgical treatments, and reports no new clinical results; the authors highlight the need for more research on long-term effects.

This study found that women treated with GnRHa for central precocious puberty had a higher prevalence of polycystic ovary syndrome in adulthood compared to those with isolated premature thelarche.