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research Insulin Administration Alters Gonadal Steroid Metabolism Independent of Changes in Gonadotropin Secretion in Insulin-Resistant Women with Polycystic Ovary Syndrome

202 citations , January 1989 in “Journal of Clinical Investigation”

Insulin changes sex hormone levels in women with polycystic ovary syndrome without affecting other hormone releases.

research Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome

40 citations , March 2016 in “The Journal of Clinical Endocrinology & Metabolism”

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

research Steroid 17β-Hydroxysteroid Dehydrogenase Deficiency in Man: An Inherited Form of Male Pseudohermaphroditism

46 citations , December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology”

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

research Menstrual Disorders in Adolescents

75 citations , June 1999 in “Pediatric Clinics of North America”

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Inhibition of 5α-Reductase Impairs Cognitive Performance, Alters Dendritic Morphology, and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

research Inhibition of 5α-Reductase Impairs Cognitive Performance, Alters Dendritic Morphology, and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

13 citations , January 2020 in “Neuroscience”

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

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community I am horny as hell due to fin.

in Finasteride/Dutasteride 225 upvotes 2 years ago

Some individuals taking finasteride for hair loss report increased libido and frequent masturbation, with no immediate hair regrowth but darker hair appearance. A dermatologist explains that finasteride may raise testosterone levels temporarily, which could lead to increased sex drive in some people.

community This could be it!!! New treatment increase hair 500%

in Research/Science 343 upvotes 1 month ago

Clascoterone (Breezula) shows a potential 500% increase in hair growth, possibly outperforming minoxidil and finasteride. It is in advanced trials, with hopes for FDA approval, but cost and side effects are concerns.

community Ru, Stemoxydine or Alfatradiol? What has your experience been with any of these 3?

in Treatment 3 upvotes 2 years ago

The user is seeking advice on which treatment to add to their current regimen for male pattern baldness. They have previously tried Dutasteride, Nizoral, and oral Minoxidil, but experienced continued hair loss. They are specifically asking for experiences with RU58841, Stemoxydine, or Alfatradiol.

community Takes time my friends, years in fact

in Satire 53 upvotes 2 years ago

The conversation discusses long-term hair loss treatment, with one person seeing hair darkening after 3 years using Minoxidil, Finasteride, and Dutasteride, and others sharing their shorter-term experiences with similar treatments. They emphasize that hair regrowth takes time and to not expect quick results.

community How does hair loss and recovery work?

in Chat 12 upvotes 1 year ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

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