1 citations
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December 2019 in “Frontiers in endocrinology” This study found that high prepubertal and pubertal androgen levels, originating from both adrenal and gonadal secretion, were negatively associated with adult height outcomes in males with Silver-Russell syndrome.
May 2017 in “Endocrine Abstracts” This study found that men with early-onset androgenetic alopecia who also met criteria for the male PCOS-equivalent may have impaired gonadal steroidogenesis, suggesting increased risk of future gonadal dysfunction.
26 citations
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March 1981 in “Clinical Endocrinology” In this study, researchers found that oestrogen did not increase adrenal androgen secretion in children with premature adrenarche or in adolescents with gonadal dysgenesis undergoing oestrogen replacement therapy.
3 citations
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May 2023 in “Endocrine Abstracts” This study identified three subgroups of women with PCOS with distinct androgen profiles, finding that the subgroup with adrenal-derived androgen excess had the highest insulin resistance and rates of hirsutism and hair loss.
207 citations
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September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” The study found that reducing testosterone in male mice through castration or androgen antagonism significantly accelerated wound healing by decreasing inflammation, suggesting a potential therapeutic target for impaired healing in elderly men.