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research Prostaglandin D2 Enhances Testosterone Metabolism by ROS-Mediated Altered Redox Potential in Keratinocytes

September 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

research Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition

4 citations, February 2022 in “Frontiers in molecular biosciences”

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

research PRX102 Participates in Root Hairs Tip Growth of Rice

1 citations, November 2023 in “Rice”

PRX102 is essential for rice root hair growth by helping transport substances to the tips.

research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

38 citations, June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

research Long-Term Administration of Triterpenoids From Ganoderma Lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice

9 citations, May 2021 in “Frontiers in aging neuroscience”

Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.

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community Anything you use without scientific backing, just trusting your gut?

in Research/Science 12 upvotes 2 years ago

The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 743 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community I will have it cured by morning

in Research/Science 370 upvotes 1 year ago

Researching the cause of hair loss and treating it by preventing DHT in the scalp with medication such as finasteride or dutasteride, estrogen, minoxidil, dermarolling, and possible topical antiandrogens.

community Obviously, all of us who are serious take antiandrogens and growth stimulants - what else are you doing lifestyle wise, dietary wise, and regiment wise to maximize your results?

in Treatment 21 upvotes 5 months ago

The user follows a hair loss treatment routine including Propecia, oral minoxidil, ketoconazole, and plans to switch to dutasteride. They also focus on lifestyle changes, dietary supplements, and are considering laser therapy.

community One year progress on fin and min

in Progress Pictures 176 upvotes 6 months ago

A user shared one-year progress using finasteride and minoxidil for hair loss at age 42. Suggestions included adding dermastamping, microneedling, and considering a hair transplant for further improvement.

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