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Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2

research Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2

6 citations, September 2023 in “Experimental physiology”

A special receptor in sensory nerve endings helps control how they respond to stretching.

research Glutamate Transporter SLC1A3 Mediates Inter-Niche Stem Cell Activation During Skin Growth

34 citations, April 2018 in “EMBO journal”

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

research Synaptic-Like Vesicles and Candidate Transduction Channels in Mechanosensory Terminals

11 citations, July 2015 in “Journal of Anatomy”

SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.

research Modulating Mechanosensory Afferent Excitability by an Atypical mGluR

1 citations, June 2015 in “Journal of anatomy”

A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.

research Locally Synthesized 17-Beta-Estradiol Reverses Amyloid-Beta-42-Induced Hippocampal Long-Term Potentiation Deficits

January 2024 in “International journal of molecular sciences”

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

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community Organic Self Tanner on bald Scalp?

in Shaved/buzzed 1 upvotes 1 year ago

The user is using topical minoxidil and finasteride, along with daily derma rolling, and is considering using an organic self-tanner on their shaved scalp. They seek advice on whether the self-tanner's ingredients could harm hair regrowth.

community What can I use to prepare a lotion that doesn't irritate my scalp or make my hair sticky? (Want to experiment with metformin and Alpha Keto glutarate)

in Product 2 upvotes 1 year ago

The conversation is about a user who tried dissolving a metformin pill in water for hair treatment but faced issues with hair sticking together. The user is seeking advice on preparing a non-irritating, non-sticky lotion at home, possibly experimenting with metformin and Alpha Keto glutarate.

community Guide To Finasteride and Avoiding Side Effects

in Finasteride/Dutasteride 25 upvotes 2 years ago

The conversation provides a guide on using finasteride for hair loss, suggesting to start with a quarter of a 1mg pill daily after ensuring estradiol levels are within a specific range, and potentially increasing the dose if no side effects occur. It also recommends supplements like DIM, Calcium d-glucarate, and Zinc to manage high estradiol levels and side effects from finasteride.

community Did pre-tests before starting finasteride, turns out I have abnormally high estrogen

in Finasteride/Dutasteride 1 upvotes 3 months ago

A 23-year-old with high estrogen levels is considering starting finasteride for hair loss and plans to use a low dose topical treatment while also seeking to lower estrogen levels. They will consult an endocrinologist for further guidance.

community How many mgs of zinc should I take while taking fin? I want to potentially offset side effects but not ruin the effectiveness of fin. I take .5 mg fin daily

in Chat 13 upvotes 3 years ago

A user asks about the appropriate zinc dosage to offset side effects while taking 0.5 mg of finasteride daily. Responses suggest zinc has a minor effect on hormones compared to finasteride.

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