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research Clinical and biochemical changes during high-dose glucocorticoid therapy in patients with pemphigus vulgaris (a comparative study with endogenous hypercortisolism)

April 2026 in “Almanac of Clinical Medicine”

In this study, pemphigus vulgaris patients treated with high-dose prednisolone developed symptoms similar to those seen in corticosteroma, such as weight gain and muscle weakness, with increased risks of arterial hypertension and glucose metabolism disorders after 6 months of therapy.

research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance

4 citations , October 2007 in “Dermatologic Clinics”

This review discusses the roles of glucocorticoid and sex hormone receptors in the skin and their clinical importance, but reports no new research findings.

research Primary Generalized Glucocorticoid Resistance and Hypersensitivity

48 citations , January 2011 in “Hormone Research in Paediatrics”

This review discusses the molecular basis and clinical implications of primary generalized glucocorticoid resistance and hypersensitivity, attributing them to mutations in the human glucocorticoid receptor gene, and reports no new clinical findings.

research Generalised Glucocorticoid Resistance

January 2008 in “US endocrinology”

This paper describes the hGRα gene structure and its expression, focusing on the functional properties of the longest GRα isoform, but reports no new results.

research Management Approaches to Congenital Adrenal Hyperplasia in Adolescents and Adults; Latest Therapeutic Developments

7 citations , December 2011 in “InTech eBooks”

This review discusses current and evolving treatment strategies for congenital adrenal hyperplasia in adolescents and adults, focusing on glucocorticoid and mineralocorticoid therapy and the management of insulin resistance, without reporting new clinical results.

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community There’s nothing better on the horizon [RANT]

22 upvotes 2 months ago

There is skepticism about new hair loss treatments, with the belief that current options like minoxidil, finasteride, and hair transplants are the best available. Concerns are raised about the systemic side effects of androgen-related treatments, even those marketed as topical, and doubts about the effectiveness of emerging treatments like clascoterone.

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