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Risk of Suicide, Hair Loss, and Aspiration with Glucagon-Like Peptide 1 Receptor Agonists: A Real-World Pharmacovigilance Study from the FAERS Database

research Risk of Suicide, Hair Loss, and Aspiration with Glucagon-Like Peptide 1 Receptor Agonists: A Real-World Pharmacovigilance Study from the FAERS Database

November 2024 in “Circulation”

GLP1-RAs may have higher reports of suicide and hair loss, but no strong evidence links them to these issues.

From Evidence to Practice: Insights from the Multidisciplinary Team on the Optimal Integration of GLP-1 Receptor Agonists in Obesity Management Services

research From Evidence to Practice: Insights from the Multidisciplinary Team on the Optimal Integration of GLP-1 Receptor Agonists in Obesity Management Services

August 2024 in “Nutrition Bulletin”

GLP-1 receptor agonists help with weight loss but need to be combined with other treatments for best results.

research GLP-1 Receptor Agonists and Skin Health: Exploring Dermatologic Side Effects and Therapeutic Interventions

June 2025

GLP-1 receptor agonists can cause skin and hair issues due to rapid weight loss, but these can be managed with proper care and treatments.

Short-Term Combined Treatment With Liraglutide and Metformin Leads to Significant Weight Loss in Obese Women With Polycystic Ovary Syndrome and Previous Poor Response to Metformin

research Short-Term Combined Treatment With Liraglutide and Metformin Leads to Significant Weight Loss in Obese Women With Polycystic Ovary Syndrome and Previous Poor Response to Metformin

116 citations , December 2013 in “European journal of endocrinology”

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery

26 citations , December 2016 in “Pharmacology & Therapeutics”

New drugs for heart disease may be developed from molecules secreted by stem cells.

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community He used Dutasteride for 20 years. Interview

in Treatment 112 upvotes 10 months ago

Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.

community Hot Take: Betting on PP405 can backfire

in Research/Science 83 upvotes 3 months ago

PP405 is seen as promising but uncertain, with users advised to continue using existing treatments like minoxidil and finasteride. Concerns include its cost, availability, and interaction with hair transplants, while some hope it could complement current treatments.

community New warning by FDA on topical finasteride

in Research/Science 194 upvotes 5 months ago

The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.

community Any treatments in development that could theoretically give complete regrowth?

in Research/Science 8 upvotes 5 months ago

New hair loss treatments like PP-405, AMP-303, and SCUBE3 are being discussed, but none are confirmed to fully restore hairlines. Current treatments like Minoxidil, Finasteride, and RU58841 are still widely used, with some hope for future advancements in hair regrowth.

community Did UCLA Just Cure Baldness? Check this Out!

in Research/Science 974 upvotes 8 months ago

UCLA's PP405 shows promise in reactivating dormant hair follicles for hair loss treatment but is still in clinical trials. Minoxidil and finasteride remain common treatments until PP405 becomes available.

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