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research GLP-1 Receptor Agonists: Beyond Their Pancreatic Effects

59 citations , August 2021 in “Frontiers in Endocrinology”

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

research Use of Glucagon-Like Peptide-1 Agonists in Modulating Preexisting Dermatologic Disease: A Systematic Review

September 2025 in “Cureus”

GLP-1 agonists may help treat certain skin conditions.

research Alopecia as an Emerging Adverse Effect Associated with Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss: A Scoping Review

August 2025 in “Cureus”

GLP-1 receptor agonists for weight loss may cause hair loss, especially in women.

research GLP-1 Receptor Agonists and Skin Health: Exploring Dermatologic Side Effects and Therapeutic Interventions

June 2025

GLP-1 receptor agonists can cause skin and hair issues due to rapid weight loss, but these can be managed with proper care and treatments.

research Dermatologic Implications of GLP-1 Receptor Agonist Medications: A Comprehensive Review

February 2025 in “Skin Appendage Disorders”

GLP-1 receptor agonists can cause skin reactions, facial fat loss, and hair loss, but may help with wound healing and skin conditions.

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community Any treatments in development that could theoretically give complete regrowth?

in Research/Science 7 upvotes 5 months ago

New hair loss treatments like PP-405, AMP-303, and SCUBE3 are being discussed, but none are confirmed to fully restore hairlines. Current treatments like Minoxidil, Finasteride, and RU58841 are still widely used, with some hope for future advancements in hair regrowth.

community Did UCLA Just Cure Baldness? Check this Out!

in Research/Science 974 upvotes 8 months ago

UCLA's PP405 shows promise in reactivating dormant hair follicles for hair loss treatment but is still in clinical trials. Minoxidil and finasteride remain common treatments until PP405 becomes available.

community What treatment helps diffuse hair thinning from insulin resistance?

in Treatment 1 upvotes 2 years ago

The individual is experiencing hair loss due to insulin resistance (IR) and is seeking advice. They are currently using a keto diet, supplements, exercise, and plan to add metformin to their regimen.

community Will PP405 be prohibitively expensive or will it be roughly the same as fin or min?

in Research/Science 6 upvotes 1 month ago

PP405 is expected to be more expensive than finasteride and minoxidil initially due to patent protection, but not as costly as life-saving medications like Ozempic. The price may decrease after the patent expires, but initially, it might be around $100 per month, making it potentially unaffordable for many.

community Wtf have we been doing for the last 30 years

in Treatment 548 upvotes 9 months ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

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