March 2023 in “JIIS (Jurnal Ilmiah Ibnu Sina): ilmu farmasi dan kesehatan” This study concluded that the optimum biotin microemulsion hair tonic composition involves span 80 (20%), tween 80 (9.47%), and PEG 400 (5%), providing favorable viscosity and globule size.
June 2021 in “World Journal Of Advanced Research and Reviews” In this study, researchers evaluated emulsions made with natural plant extracts and oils on guinea pigs, finding that a specific hydrophilic/lipophilic balance and globule size led to a stable emulsion and stimulated hair growth.
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April 2018 in “Majalah Obat Tradisional” In this study, the FIII micro emulsion formulation of virgin coconut oil and rice bran oil showed the best results for hair growth, increasing rabbit hair length by 1.26 cm in 18 days.
June 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the stability and capillary growth-stimulating activity of emulsions made with natural plant extracts and oils in vivo on guinea pigs, finding that specific hydrophilic/lipophilic balance and globule size contribute to a stable and effective formulation.
This study found that incorporating Aloe vera and celery extract into water or oil microemulsions promoted hair growth in rats, with the water-in-oil formulation showing faster initial results.