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research The efficacy and safety of dutasteride compared with finasteride in treating men with androgenetic alopecia: a systematic review and meta-analysis

38 citations , February 2019 in “Clinical Interventions in Aging”

This meta-analysis found that dutasteride was more effective than finasteride in increasing hair count and improving photographic assessments for men with androgenetic alopecia, while both drugs had similar rates of sexual dysfunction-related adverse effects.

research The effectiveness of combination therapies for androgenetic alopecia: A systematic review and meta‐analysis

11 citations , June 2020 in “Dermatologic Therapy”

This study suggests that combination therapies including minoxidil with either finasteride, low-level laser light therapy, or microneedling are more effective than minoxidil alone for treating androgenetic alopecia.

research Comparing minoxidil-finasteride mixed solution with minoxidil solution alone for male androgenetic alopecia: a systematic review and meta-analysis of randomized controlled trials

October 2025 in “Frontiers in Medicine”

This meta-analysis found that the combination of topical minoxidil-finasteride was more effective than minoxidil alone in improving hair density, hair diameter, and global photographic assessment for male androgenetic alopecia, though larger standardized trials are needed to confirm long-term outcomes.

research Journal Review: Long-term (5-year) multinational experience with finasteride 1mg in the treatment of men with androgenetic alopecia

7 citations , May 2002 in “Hair transplant forum international”

This article reviews long-term data on the efficacy and safety of finasteride over five years but reports no new clinical results.

research Platelet-Rich Plasma In Androgenetic Alopecia:An Evidence-Based Clinical And Biological Review

January 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

This review discusses the evidence for platelet-rich plasma as a promising treatment for androgenetic alopecia, highlighting its potential benefits and favorable safety profile but noting the need for standardized protocols and larger trials.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Breezula Phase III 12-Month Data Released by Cosmo Pharma

42 upvotes 5 months ago

Clascoterone 5% topical solution is effective and safe for long-term use in treating male pattern hair loss. Cosmo Pharma aims for EU and US approval, with a potential US release in late 2027 or early 2028.

community Heads Up on Future Study: "Influence of Creatine Monohydrate Supplementation on Androgens and Global Hair Assessments"

22 upvotes 6 years ago

Creatine supplementation may increase DHT levels, potentially affecting hair loss. A study is examining this effect, with participants taking 5 grams of creatine daily for six months.

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