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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research Acne Severity and the Global Acne Grading System in Polycystic Ovary Syndrome
Acne severity in women with PCOS is linked to younger age, lower body weight, and more body hair, but not to hormone levels.
research Referee Report: Comparison Between Tazarotene 0.05% Gel and Adapalene 0.1% Gel in Acne Patients
Tazarotene gel may be more effective for acne than adapalene gel.
research Etiopathogenesis and Therapy of Acne: Epidemiological Study of Clinical Characteristics in a Population of Acne Patients and Analysis of Polymorphisms in the Androgen Receptor Gene and Cytochrome P-450 1A1 Gene
Hereditary factors affect acne duration, not severity, and late-onset acne in females has different causes.
research Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review
Oral spironolactone's effectiveness for adult female acne is not well-supported by strong evidence.
research Systematic Review on the Various Clinical Features of Polycystic Ovary Syndrome (PCOS) Patients
PCOS has many symptoms, with high androgen levels being the most common.
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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
by
nkrata
in Research
830 upvotes
1 year ago Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community The story of RU58841/ PSK3841
by
Typical-Promise-3001
in Research
622 upvotes
1 year ago RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
community Why is it "not right" to start off with Dutasteride?
The conversation discusses whether it's better to start hair loss treatment with finasteride or dutasteride. Opinions vary, but many suggest starting with finasteride due to its shorter half-life and easier management of side effects, while others argue dutasteride is more effective and has fewer side effects.
community How come topical finasteride even works at all?
Topical finasteride can effectively reduce scalp DHT by targeting local enzymes, despite less systemic impact compared to oral forms. Combining oral dutasteride with topical finasteride and minoxidil may enhance hair loss prevention, though evidence of its effectiveness is limited.
community He used Dutasteride for 20 years. Interview
Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.