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GlossaryThiazolidinediones (glitazones)

medications that increase insulin sensitivity to treat type 2 diabetes

Thiazolidinediones, also known as TZDs or glitazones, are a class of medications primarily used to treat type 2 diabetes. They work by increasing the body's sensitivity to insulin, thereby helping to control blood sugar levels. These drugs activate a specific receptor called PPAR-gamma, which influences the regulation of glucose and lipid metabolism.

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research Cardiovascular Profile of Pharmacological Agents Used for the Management of Polycystic Ovary Syndrome

4 citations, January 2019 in “Therapeutic Advances in Endocrinology and Metabolism”

Medications for PCOS don't seem to raise heart disease risk.

research Diagnosis, Management, and Associated Comorbidities of Polycystic Ovary Syndrome: A Narrative Review

April 2024 in “Curēus”

Early detection and comprehensive treatment of PCOS are crucial due to its long-term health impacts and associated risks.

research Clinical Aspects of the Metabolic Syndrome

December 2017

Losing weight and eating better are key to managing metabolic syndrome and its related conditions.

research Dunnigan-Type Familial Partial Lipodystrophy: Understanding and Treating the Syndrome

January 2017 in “Open Journal of Endocrine and Metabolic Diseases”

The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.

Improved Efficacy of Low-Dose Spironolactone and Metformin Combination Than Either Drug Alone in the Management of Women With Polycystic Ovary Syndrome: A Six-Month, Open-Label Randomized Study

research Improved Efficacy of Low-Dose Spironolactone and Metformin Combination Than Either Drug Alone in the Management of Women With Polycystic Ovary Syndrome: A Six-Month, Open-Label Randomized Study

75 citations, July 2013 in “The Journal of Clinical Endocrinology and Metabolism”

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

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