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research Inhibition of 5α-Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring

32 citations , September 2011 in “Journal of Neuroendocrinology”

Inhibiting 5α-reductase during late pregnancy shortens gestation, reduces litter size, and harms memory in rat offspring.

research Inhibition of 5α-Reductase Alters Pregnane Metabolism in the Late Pregnant Mare

7 citations , January 2018 in “Reproduction”

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

research Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review

343 citations , December 2008 in “Endocrine Reviews”

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

research Caffeine Content in Newborn Hair Correlates with Maternal Dietary Intake

8 citations , April 2020 in “European Journal of Nutrition”

Newborns' hair shows how much caffeine their mothers drank during pregnancy.

research Effects of In Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in Male Rats

118 citations , May 2003 in “Toxicological Sciences”

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

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community Certified old, at 51, balding since 25, the resurrection!

in Progress Pictures 439 upvotes 1 year ago

A 51-year-old shared progress on hair regrowth using topical Minoxidil and Finasteride over four months, noting significant improvement and plans for future hair transplants. The user emphasized the benefits of modern treatments and societal changes in attitudes towards hair loss.

community Verteporfin and Microneedling

in Treatments 1 year ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.