research Evolution of Hard Proteins in the Sauropsid Integument in Relation to the Cornification of Skin Derivatives in Amniotes
Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
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research Structure of Human Type II 5 Alpha-Reductase Gene
The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
research Case Report: A Chinese Family of Woodhouse-Sakati Syndrome With Diabetes Mellitus, With a Novel Biallelic Deletion Mutation of the DCAF17 Gene
A new mutation in the DCAF17 gene was found in a Chinese family, causing Woodhouse-Sakati syndrome and diabetes.
research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
research The Zinc Finger Protein 3 of Arabidopsis Thaliana Regulates Vegetative Growth and Root Hair Development
The zinc finger protein 3 in Arabidopsis thaliana reduces plant growth and root hair development.
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5 / 7 resultscommunity We Need A Solution For The Inflammatory Response related To AGA
by
ANDR0GENE
in Research/Science
16 upvotes
5 months ago The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.
community M18 Is it smart to start with minox only?
by
Nettspend
in General
126 upvotes
2 months ago An 18-year-old is considering starting minoxidil for hair loss due to a receding hairline but is hesitant about using finasteride due to age and lack of health insurance. A suggestion was made to use topical finasteride and minoxidil, along with lifestyle changes like exercise and cold showers.
community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments
by
diego8895
in Research/Science
14 upvotes
4 years ago Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.
community How is it possible for someone to be a non responder to ORAL minoxidil?
by
FlochTheDestroyeer
in Minoxidil
66 upvotes
9 months ago Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.
community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found
by
Additional_Rough_968
in Research/Science
47 upvotes
2 years ago The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.