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GlossaryGene Sequencing

process of determining the exact order of DNA nucleotides

Gene sequencing, also known as DNA sequencing or genetic sequencing, is the process of determining the exact order of nucleotides within a DNA molecule. This technique allows scientists to read the genetic information encoded in an organism's DNA, which is crucial for understanding genetic disorders, evolutionary biology, and personalized medicine.

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Whole-Genome Sequencing of Eight Goat Populations for the Detection of Selection Signatures Underlying Production and Adaptive Traits

research Whole-Genome Sequencing of Eight Goat Populations for the Detection of Selection Signatures Underlying Production and Adaptive Traits

92 citations, December 2016 in “Scientific Reports”

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

research Whole Genome Sequencing Analysis of Alpaca Suggests TRPV3 as a Candidate Gene for the Suri Phenotype

February 2024 in “BMC genomics”

The TRPV3 gene variant may cause the long-haired suri alpaca coat.

Tracing Selection Signatures in the Pig Genome Provides Evidence for Selective Pressures on a Unique Curly Hair Phenotype in Mangalitza

research Tracing Selection Signatures in the Pig Genome Provides Evidence for Selective Pressures on a Unique Curly Hair Phenotype in Mangalitza

8 citations, December 2020 in “Scientific reports”

Selective breeding caused the unique curly hair in Mangalitza pigs.

research Current Genetics in Hair Diseases

1 citations, February 2013 in “InTech eBooks”

Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

research Cost-Effectively Dissecting the Genetic Architecture of Complex Wool Traits in Rabbits by Low-Coverage Sequencing

1 citations, March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Low-coverage sequencing is a cost-effective way to identify genes related to wool traits in rabbits.

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community How do we only have two treatments to combat hair loss at this point in time?

in Chat 211 upvotes 1 year ago

The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 22 upvotes 3 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Anyone else freaking out over their barber using those thinning scissors

in Chat 89 upvotes 1 month ago

Thinning scissors can worsen the appearance of already thin hair. Some recommend being clear with barbers and using Minoxidil for hair loss.

community 2 years Fin + Minoxidil Regrowth

in Finasteride/Dutasteride 113 upvotes 5 months ago

A user shared their two-year progress using 2.5mg finasteride daily and minoxidil twice daily, recently adding topical dutasteride. Another user questioned the high finasteride dosage, noting no benefits over 1mg.

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