research Female Androgenic Alopecia
This study found that women with female pattern baldness had a marked increase in the 3α,17β-androstanediol glucuronide/sex hormone binding globulin ratio and low serum sex hormone binding globulin.
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5 / 1000+ resultsresearch Female androgenic alopecia. The 3 alpha,17 beta-androstanediol glucuronide/sex hormone binding globulin ratio as a possible marker for female pattern baldness
This study found that women with female pattern baldness often had a higher ratio of 3 alpha,17 beta-androstanediol glucuronide to sex hormone-binding globulin and lower serum sex hormone-binding globulin, possibly indicating minimal androgen excess.
research Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege
This study demonstrated that disrupting EGFR signaling in mice leads to immune sensitivity compromising the hair follicle's protective environment, but JAK1/2 inhibition can restore this immune privilege and stimulate hair growth, suggesting a potential therapy for scarring hair loss diseases like cicatricial alopecia.
research 9 Pilosebaceous physiology in relation to hirsutism and acne
This review explores how androgens and growth hormone influence the development of terminal hairs and sebaceous glands, attributing variability in hirsutism and acne to differing genetic sensitivities to androgens, but reports no new experimental data.
research The Biology and Genomics of Human Hair Follicles: A Focus on Androgenetic Alopecia
This review outlines the functional anatomy, pathology, and molecular mechanisms of androgenetic alopecia, emphasizing the need for multi-omics approaches to better understand this condition's biology.
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5 / 303 resultscommunity Creatine & Hair Loss — My Personal Experience (And a Bit of Simple Math)
Creatine may accelerate hair loss in those genetically predisposed, with some users reporting increased shedding while taking it and improvement after stopping. Some users use treatments like finasteride and minoxidil, while opinions on creatine's impact vary.
community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights
PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.
community Temporalis Hypertrophy and hair loss
Hair loss treatments include finasteride, minoxidil, and scalp exercises. Opinions vary on the effectiveness, with some attributing hair loss to muscle tension and inflammation, while others focus on genetics and DHT.
community 24M Considering Hair Transplant. Trying What Feels Like Everything, To No Avail.
A 24-year-old male is considering a hair transplant after unsuccessful attempts with oral minoxidil, topical finasteride, ketoconazole shampoo, and lifestyle changes. He believes smoking and caffeine may worsen his hair loss and is looking into hair fibers for temporary coverage.
community Self-testing if creatine speeds up hair loss (while on treatment!)
Creatine may increase DHT levels, potentially affecting hair loss in some individuals, but opinions vary. Some users report hair loss while on creatine, while others see no effect, especially when using treatments like finasteride, minoxidil, and microneedling.
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