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research Role of Stem Cells in Skin Maintenance, Regeneration, and Repair: Focus on Epidermis and Pilosebaceous Units

September 2013 in “Experimental Dermatology”

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

research 25 Years of Epidermal Stem Cell Research

55 citations, March 2012 in “Journal of Investigative Dermatology”

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

research Lineage Analysis of Epidermal Stem Cells

57 citations, January 2014 in “Cold Spring Harbor Perspectives in Medicine”

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

research A Family Business: Stem Cell Progeny Join the Niche to Regulate Homeostasis

254 citations, January 2012 in “Nature Reviews Molecular Cell Biology”

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

research Safe Selection of Genetically Manipulated Human Primary Keratinocytes with Very High Growth Potential Using CD24

25 citations, August 2007 in “Molecular Therapy”

Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.

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community We all regret not acting on hair loss sooner. What is something else we can prevent if we act now?

in Chat 94 upvotes 1 year ago

The conversation discusses the importance of early action in various aspects of life such as healthy eating, skincare, fitness, sleep, financial planning, and career development to prevent future health issues, regret, and financial hardship. Specific treatments mentioned include using sunscreen and tretinoin for anti-aging skincare.

community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

in Research/Science 37 upvotes 2 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.

community Why is it "not right" to start off with Dutasteride?

in Finasteride/Dutasteride 60 upvotes 5 months ago

The conversation discusses whether it's better to start hair loss treatment with finasteride or dutasteride. Opinions vary, but many suggest starting with finasteride due to its shorter half-life and easier management of side effects, while others argue dutasteride is more effective and has fewer side effects.

community [SAD UPDATE] 11 Months Topical Finasteride on TrichoSol - Hair got worse - Need Opinions

in Progress Pictures 9 upvotes 8 months ago

A user expressed disappointment that their hair loss worsened after 11 months using topical finasteride with TrichoSol, despite no side effects and initial signs of improvement. They asked for advice and opinions on their treatment and alternatives, with suggestions including switching to oral finasteride or dutasteride, starting minoxidil, and addressing their seborrheic dermatitis with different shampoos or medical advice.

community Fun thought experiment about halting hair loss permamently

in Research/Science 58 upvotes 7 months ago

A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

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