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Therapeutic Hotline: Genetic Variations in the Androgen Receptor Gene and Finasteride Response in Women with Androgenetic Alopecia Mediated by Epigenetics

research THERAPEUTIC HOTLINE: Genetic variations in the androgen receptor gene and finasteride response in women with androgenetic alopecia mediated by epigenetics

16 citations , March 2011 in “Dermatologic Therapy”

This study suggests that genetic variants in the androgen receptor gene may predict which postmenopausal women with hair loss respond to finasteride therapy.

research COVID-19: The question of genetic diversity and therapeutic intervention approaches

4 citations , January 2021 in “Genetics and Molecular Biology”

This review discusses various strategies proposed to control COVID-19 and highlights challenges related to human and viral genetic variability but reports no new findings.

research 314 Molecular genetic dissection of ILVEN leads to successful targeted therapy

September 2019 in “Journal of Investigative Dermatology”

This study found that mosaic mutations in the CARD14 gene are linked to inflammatory linear verrucous epidermal naevus in two patients, who experienced significant improvement with the IL12/IL23 inhibitor Ustekinumab.

Immune Signatures of Psoriasis: Comparison of Genetic Expression Profiles in Psoriasis Patients After Therapy with Biologic Agents

research Immune signatures of psoriasis: Comparison of genetic expression profiles in psoriasis patients after therapy with biologic agents

May 2015 in “Journal of The American Academy of Dermatology”

This study suggests that blood microarray biomarkers may help predict individual treatment response in psoriasis patients, highlighting a distinct blood signature related to inflammation, interferon, and myeloid lineage transcripts.

research Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies

February 2026 in “Frontiers in Pharmacology”

This review suggests a shift toward genetically informed treatments for male pattern hair loss by integrating genetic insights and pharmacogenetic markers into therapeutic decision-making.

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Community Join

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community Need Help Please! It's about Exosome therapy and my hair fall. If you have any questions, feel free to ask!

in Treatment 1 upvotes 6 months ago

A person experienced hair loss due to stress, hormonal changes, and possibly genetics, and tried treatments like minoxidil, finasteride, and dutasteride. They are now considering exosome therapy but are unsure about its effectiveness and which dermatologist to trust.

community Hair Loss Factors in Moms: Analyzing Hormonal Changes, Stress, Genetics, and More

4 upvotes 3 years ago

Hair loss in moms can be caused by hormonal changes, stress, genetics, and nutritional deficiencies. Solutions include hair toppers, Minoxidil, PRP therapy, and a healthy diet with supplements.

community KX 826 x Hair Loss - The Last Dance

8 upvotes 4 years ago

The conversation humorously discusses hair loss treatments, mentioning Minoxidil, finasteride, and RU58841. It suggests that affordable genetic therapy could be the ultimate solution.

community Chromosome 20’s balding effects and why fin likely isn’t working for some.

in Treatment 96 upvotes 1 year ago

Finasteride is effective for DHT/AR-driven hair loss but not for chromosome 20-driven cases, where treatments like minoxidil, prostaglandin analogs, and low-level laser therapy may be more beneficial. Genetic testing can help determine the underlying cause of hair loss to tailor treatment effectively.

community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 11 months ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

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Learn

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learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn SCUBE3

a signaling molecule from dermal papilla cells being actively researched

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Vitamin B1

Thinning hair over time? It might not just be genetics: lack of B1 and B2 could be silently working against you. There is no verified human trial showing that B1 or B2 deficiency causes thinning hair or that correcting it regrows hair; a 2019 review concludes the role of micronutrients in hair loss is real but unclear and still needs controlled trials.

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