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research Genetic regulation of the androgen receptor—A study of testicular feminization in the mouse

20 citations , March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry”

This study found a direct correlation between the testicular feminization gene and decreased androgen receptor activity, potentially explaining the androgen insensitivity in affected individuals.

research Differences in male and female pattern hair loss based on androgens, estrogen, iron, vitamin D, lipid metabolism, and genetic regulation

July 2026 in “Journal of Cutaneous and Aesthetic Surgery”

This review suggests that female and male hair loss patterns differ due to hormonal influences, metabolic factors, and genetic loci, with female pattern hair loss potentially occurring without androgen influence, highlighting the need for distinct clinical management approaches.

research Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies

15 citations , June 2020 in “Experimental Dermatology”

This review discusses recent genetic findings on hormonal signaling pathways in androgenetic alopecia, reporting no new study results but highlighting the need for further investigation.

research Unequal Protection Under the Law: Why FDA Should Use Negotiated Rulemaking to Reform the Regulation of Generic Drugs

1 citations , January 2013 in “Scholar Commons (University of South Carolina)”

This article discusses the regulatory gap in updating labeling responsibilities for generic drugs and argues for the FDA to use negotiated rulemaking to develop more effective drug regulations, but provides no new empirical results.

research Genetic and biochemical aspects of the synthesis of keratin by hair follicles

5 citations , February 2007 in “Cytology and genetics”

This review summarizes advances in understanding the genetic regulation of keratin synthesis in hair follicles and reports no new experimental results.

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Community Join

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community Indian friends - which generic oral minoxidil brands would you recommend?

in Minoxidil 14 upvotes 1 month ago

The conversation is about recommendations for generic oral minoxidil brands from India, with users suggesting brands like Dr. Reddy's Mintop, Intas Lonitab, and Asher Pharmaceuticals' Minoxihead. Users also discuss other treatments like finasteride and dutasteride, with some expressing concerns about brand reputation and supplier reliability on IndiaMart.

community Modifiability of the aging process

17 upvotes 4 months ago

Hair loss is largely influenced by genetics, with treatments like finasteride, minoxidil, and RU58841 being used to manage it. Despite healthy lifestyles, hair loss can still occur, highlighting the complex relationship between genetics, health, and aging.

community Losing the genetic lottery - venting

in Chat 67 upvotes 4 months ago

The user is experiencing hair loss and has tried various treatments including topical and oral finasteride, minoxidil, dutasteride, and ketoconazole, but continues to lose hair. They are considering alternative solutions like hair systems due to the lack of improvement and a scalp condition called CVG.

community Have people with aggressive balding genetics genuinely had any results after applying any natural remedies ie:rosemary oil,coconut oil,Onion Juice etc

in Research/Science 42 upvotes 2 years ago

Natural remedies like rosemary oil, coconut oil, and onion juice are generally seen as less effective compared to medical treatments like finasteride, minoxidil, and microneedling. Some users believe natural oils can help, but modern medicine is often more reliable.

community Does someone like Prince William have such intense balding genetics that not even Dutasteride can save them?

in Chat 113 upvotes 1 year ago

Some men have strong balding genetics that treatments like Dutasteride, Minoxidil, or Finasteride may not fully address. Early intervention is believed to help, but many accept hair loss without treatment.

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Learn

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learn Ketoconazole

Is it better to buy a ketoconazole shampoo from a pharmacy or a brand name one? Approved generic and brand-name ketoconazole shampoos carry the same active ingredient at the same strength, and regulators require a generic to be shown equivalent to the product it copies; no published head-to-head trial compares them, and generics are usually the cheaper option.

learn SCUBE3

a signaling molecule from dermal papilla cells being actively researched

learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Stem Cell Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Vitamin B1

Thinning hair over time? It might not just be genetics: lack of B1 and B2 could be silently working against you. There is no verified human trial showing that B1 or B2 deficiency causes thinning hair or that correcting it regrows hair; a 2019 review concludes the role of micronutrients in hair loss is real but unclear and still needs controlled trials.

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