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5 / 5 resultslearn HMI-115
much-hyped research compound targeting prolactin receptor in scalp
learn SCUBE3
a signaling molecule from dermal papilla cells being actively researched
learn Alopecia Areata
autoimmune disorder causing patchy hair loss
learn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
Research
5 / 1000+ resultsresearch Phenotypic Heterogeneity in Human Genetic Diseases: Ultrasensitivity-Mediated Threshold Effects as a Unifying Molecular Mechanism
Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
research Mechanical Anisotropy of Hair Affected by Genetic Diseases Highlights Structural Information Related to Differential Crosslinking in Keratins
research Analysis of the Human Diseasome Using Phenotype Similarity Between Common, Genetic, and Infectious Diseases
The study found that diseases can be grouped by symptoms and that the accuracy of predicting disease-related genes varies with the data source.
research Proceedings of the First International Scientific Practical Online Conference on Human Genetics and Genetic Diseases: Problems and Development Perspectives
research Genetic Disorders and Defects in Vitamin D Action
Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.
Community Join
5 / 1000+ resultscommunity How do we only have two treatments to combat hair loss at this point in time?
The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.
community Am I balding? Should I just shave it off?(M86)
A user humorously questions if they should shave their head due to hair loss, mentioning Ronald Reagan's impressive hair genetics. Replies include jokes and comments about jealousy and distrust towards older individuals with full heads of hair.
community A new meta-analysis of 23 studies has confirmed that 5 milligrams a day of oral dutasteride had the highest probability of reducing male hair loss, followed by 5 milligrams a day of oral finasteride, followed by 5 milligrams of oral minoxidil, followed by 1 milligram a day of oral finasteride
Oral dutasteride (0.5mg) is most effective for male hair loss, followed by oral finasteride (5mg), oral minoxidil (5mg), and oral finasteride (1mg). Different treatments have benefits and side effects, and results don't apply to women's hair loss.
community UPDATE: The theory that explains everything. Please help me make this big!
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.
community Kevin Mann(Haircafe) is the GOAT
A user praised Kevin Mann for his hair loss advice, crediting finasteride and minoxidil with tretinoin for saving their hair. Other users shared similar experiences and expressed frustration over Mann's channel being affected by past controversies.