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research Gender Differences in the Regulation of Blood Pressure

1231 citations , May 2001 in “Hypertension”

This review discusses the potential mechanisms by which androgens may elevate blood pressure, particularly through impacts on the renin-angiotensin system, but reports no new experimental results.

research Gender Differences in Mouse Skin Morphology and Specific Effects of Sex Steroids and Dehydroepiandrosterone

168 citations , January 2005 in “Journal of Investigative Dermatology”

Male and female mice have different skin thickness, and hormones affect their skin and hair growth differently.

research Gender differences in skin: A review of the literature

152 citations , December 2007 in “Gender Medicine”

This review discusses recent advances in understanding gender differences in skin and their implications for dermatologic diseases, but it reports no new experimental results; ongoing research is necessary for translating these insights into clinical practice.

research Gender differences in patients with COVID-19: a narrative review

91 citations , May 2020 in “Monaldi Archives for Chest Disease”

This narrative review explores gender differences in the epidemiology, risk factors, and effects of COVID-19, emphasizing the need for further analysis using comprehensive gender indicators to shape effective public health strategies and policies.

research Gender Differences in Cardiac Hypertrophy

27 citations , February 2020 in “Journal of Cardiovascular Translational Research”

This review discusses the role of sex hormones in cardiac hypertrophy and notes that estrogen provides protection against hypertrophy in pre-menopausal women, which is reduced after menopause but partially restored with estrogen therapy.

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Community Join

5 / 146 results

community 2 months of difference with estradiol and spiro (4 months total w/ estradiol & spiro; 4 years of minoxidil and finasteride) (you should not take estradiol or spiro if you look manly and want to continue looking manly)

122 upvotes 1 year ago

Hair regrowth using estradiol, spironolactone, minoxidil, and finasteride, showing significant improvement over four years. HRT is not advised for cis men solely for hair loss due to feminizing effects.

community Sorry yall I cheated 😵‍💫 1 year fin + hrt

682 upvotes 9 months ago

Hair regrowth and gender transition using finasteride, estrogen, and spironolactone. Significant hair regrowth and personal transformation were achieved through hormone replacement therapy.

community Is Amazon Minoxidil 5% Legit? Never seen it before

35 upvotes 1 month ago

Amazon's Minoxidil 5% is considered legitimate by some users, though availability varies by country. Users discuss differences in application for men and women, with some expressing skepticism about Amazon's products and recommending tests for authenticity.

community I don’t understand this, is he equating taking Fin with being on HRT?

303 upvotes 1 year ago

The conversation is about using finasteride and testosterone replacement therapy (TRT) for hair loss and their role in gender-affirming care. It debates whether these treatments are considered hormone replacement therapy (HRT) and their implications for both cisgender and transgender individuals.

community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?

in Finasteride/Dutasteride 757 upvotes 1 year ago

Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.

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Learn

3 / 801 results

learn Cyproterone

Is cyproterone safe to use during gender transition? Regulators and a large French cohort study link higher-dose, long-term cyproterone acetate to meningioma, and its label also lists liver-enzyme and mood effects — so it is not a drug anyone should call safe in the abstract, and its use in gender-affirming care is a prescriber's decision with monitoring.

learn Clascoterone

Can I use clascoterone if I'm undergoing gender-affirming hormone therapy? No published clinical trial has tested clascoterone in people on gender-affirming hormone therapy, so its safety in that group is unknown. The FDA label reports low systemic exposure and no described effect on blood testosterone, but it also records HPA-axis suppression and raised potassium in a small minority of subjects.

learn Setipiprant

Can Setipiprant be used safely by women or people undergoing gender transition? Setipiprant's safety for women and those in transition is not well-studied.

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Clinics

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