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research Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence

77 citations , March 2021 in “Nature”

In this study, increased corticosterone from chronic stress prolonged hair follicle stem cell quiescence in mice, inhibiting regeneration, but restoring Gas6 expression overcame this inhibition.

research N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting

76 citations , June 2015 in “Journal of biomedical science”

This study demonstrated that dominant mutations in mouse gasdermin A3 disrupt mitochondrial oxidative stress regulation, suggesting a gain-of-function effect on epidermal differentiation.

research Risk factors for sebaceous gland diseases and their relationship to gastrointestinal dysfunction in Han adolescents

66 citations , September 2008 in “The Journal of Dermatology”

This study found that gastrointestinal dysfunction is a significant risk factor for sebaceous gland diseases in adolescents, with correlations observed between these conditions and various GI symptoms.

research Determination of estrone and 17β-estradiol in human hair by gas chromatography–mass spectrometry

64 citations , January 2000 in “The Analyst”

This study describes an efficient gas chromatography-mass spectrometry method for detecting estrone and 17 beta-estradiol concentrations in hair, finding differing levels in male and female samples.

Phytochemical Analyses of Ziziphus Jujuba Mill. Var. Spinosa Seed by Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry and Gas Chromatography-Mass Spectrometry

research Phytochemical analyses of Ziziphus jujuba Mill. var. spinosa seed by ultrahigh performance liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry

38 citations , January 2013 in “Analyst”

This study identified the main secondary metabolites in Ziziphus jujuba seeds and confirmed that UPLC-MS/MS and GC-MS effectively demonstrate their pharmaceutical quality.

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community The ending of alopecia? Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence

63 upvotes 4 years ago

Corticosterone inhibits GAS6, affecting hair follicle stem-cell activity, with potential implications for stress-related hair loss. Ashwagandha and Vitamin K are suggested for reducing cortisol, but their effectiveness is debated.

community Anyone else’s loved ones just blatantly gaslight you over your hair ?

in Finasteride/Dutasteride 196 upvotes 3 years ago

User discusses resentment towards people who dismissed their hair loss concerns and continued to do so even after a specialist confirmed it. Others share similar experiences and discuss the impact of hair loss on self-esteem and societal perceptions.

community It's very ironic that many guys will gaslight you that your hair loss does not matter but unconsciously in another sentence they will recommend you a giant compensation mechanism like becoming a bodybuilder or a multimillionaire.

in Chat 419 upvotes 1 year ago

Hair loss matters, but focusing on self-improvement like working out, using treatments like minoxidil and finasteride, and building confidence can help. People often suggest extreme solutions like becoming a millionaire or bodybuilder, but practical steps are more beneficial.

community Relax to grow more hair. Study title: Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence

6 upvotes 5 years ago

Relaxation may promote hair growth by reducing corticosterone, which affects hair follicle stem cells. Corticosteroids are used for alopecia areata, but their long-term use for androgenic alopecia is uncertain.

community Any clinical study on cysteine alone for hair loss?

6 upvotes 1 year ago

The conversation discusses the lack of clinical studies on cysteine alone for hair loss, with the original poster already using medications like Minoxidil and finasteride. Suggestions include trying 2ddr as a growth stimulant, though concerns about side effects like gas are mentioned.

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