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3 / 3 resultslearn Gamma linolenic acid
learn Valproic acid
an anticonvulsant repurposed for hair loss via histone inhibition
Research
5 / 460 resultsresearch Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
![An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement](/images/research/3a2c1a11-ce1b-4fb5-a763-d6a8a39b8310/small/25858.jpg)
research An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
![Dermatologic Toxicities Associated with Chronic Gamma-Secretase Inhibitor Treatment for Desmoid Tumor](/images/research/5464415e-02c3-425b-93bf-d60b69641f5b/small/35090.jpg)
research Dermatologic Toxicities Associated with Chronic Gamma-Secretase Inhibitor Treatment for Desmoid Tumor
Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.
research Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease
Hidradenitis suppurativa might be a type of autoinflammatory skin disease.
research Hairy Tale of Signaling in Hair Follicle Development and Cycling
Hair growth and development are controlled by specific signaling pathways.
Community Join
5 / 14 resultscommunity HLT Megathread on HMI-115 (key takeaways in comments)
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
community Coming up to 4 months of minoxidil only 2 weeks of fin
A user experienced significant hair regrowth using minoxidil for four months and recently started finasteride. Suggestions include continuing treatment, possibly shaving for a better look, and adding microneedling to enhance results.
community Does Evening primrose oil have a negative effect on a person if they’re taking it alongside finasteride and minoxidil?
A user is concerned about taking evening primrose oil alongside finasteride and minoxidil due to its potential effects on hormonal balance and DHT inhibition. They seek advice on whether to continue the supplement or if their worries are unfounded.
community Vitamin E
Vitamin E was discussed as a treatment for hair shedding, with a specific form mentioned. A user shared a link to a study and started taking the Vitamin E variants used.
community [Discussion] Interesting read on Vitamin E for hair loss I found
The conversation discusses using Vitamin E, Minoxidil, finasteride, and RU58841 for hair loss treatment. The link provided offers more information on the benefits of Vitamin E for hair loss.