learn Valproic acid
an anticonvulsant repurposed for hair loss via histone inhibition
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research Hormones and Absence Epilepsy
Stress and hormones like progesterone can affect absence seizures, but their effects change with different life stages.
research Changes in Functionality, Expression of Extrasynaptic GABAA Receptors, and Synaptic Plasticity in the Rat Hippocampus During Pregnancy and Postpartum.
During late pregnancy in rats, hormonal changes increased certain GABAA receptors in specific brain cells.
research Neuroactive Steroids Inhibit Spinal Reflex Potentiation by Selectively Enhancing Specific Spinal GABAA Receptor Subtypes
Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.
research GABAA Receptor Modulation by Neurosteroids in Models of Temporal Lobe Epilepsies
Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
research Relating Neurosteroid Modulation of Inhibitory Neurotransmission to Behavior
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
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5 / 52 resultscommunity 1 year fin 1mg and minox. can see some density reclaimed
User shared 1-year progress using finasteride 1mg and minoxidil, regaining hair density. Others praised the improvement and asked about side effects and additional treatments.
community Why is Kevin Mann (Haircafe) Hated?
Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.
community Finasteride vs Dutasteride: The Science
The conversation compares Finasteride and Dutasteride for hair loss treatment, discussing their effectiveness and side effects. Users share personal results and consider combining treatments like Dutasteride with RU58841.
community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering
Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.
community Would there be ANY reason to still take 5AR inhibitors if pyrilutamide does what is intended?
A potential new treatment for hair loss, Pyrilutamide, and the discussion of whether or not people should still be taking traditional treatments like Minoxidil and Finasteride with it.