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Gamma-Aminobutyric Acid Promotes the Inhibition of Hair Growth Induced by Chronic Restraint Stress

research γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress

1 citations , January 2023 in “Life sciences”

This study demonstrated that elevated GABA levels can worsen stress-induced hair growth inhibition in mice, while GABAA antagonists like ginkgolide A may help alleviate these effects.

research Sodium Valproate Improves Skin Flap Survival via Gamma-Aminobutyric Acid and Histone Deacetylase Inhibitory System

8 citations , October 2019 in “The Journal of surgical research/Journal of surgical research”

This study demonstrated that sodium valproate accelerates skin healing and reduces necrosis in a rat model of skin flap potentially through mechanisms involving GABA and histone deacetylase pathways.

research Participation of GABAA, GABAB receptors and neurosteroids in toluene-induced hypothermia: Evidence of concentration-dependent differences in the mechanism of action

17 citations , October 2012 in “European Journal of Pharmacology”

This study found that inhaling toluene reduces core temperature in mice, with GABA receptors and neurosteroids involved at 4000 ppm, but different mechanisms contributing at 6000 ppm.

research Involvement of neurosteroids in the anxiolytic-like effects of AC-5216 in mice

66 citations , January 2008 in “Pharmacology Biochemistry and Behavior”

AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.

research Role of Neurosteroidogenic Pathways in the Antiseizure Activity of Midazolam in the 6‐Hz and Kindling Models of Epilepsy

April 2015 in “The FASEB Journal”

This study found that the antiseizure activity of midazolam primarily occurs through synaptic GABA-A receptors, with no significant involvement of endogenous neurosteroids or extrasynaptic receptors.

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community 5 years post hair transplant, 3 months on minoxidil only

326 upvotes 8 months ago

The user had a hair transplant five years ago and started using minoxidil three months ago. Commenters recommend adding finasteride or other DHT blockers to prevent further hair loss and maintain results.

community Dutasteride users- when and how did it go for you?

in Finasteride/Dutasteride 58 upvotes 9 months ago

Dutasteride can stabilize or improve hair loss but may cause side effects like depression and anxiety. Users often switch from finasteride to dutasteride for stronger results, with varied experiences in shedding and regrowth.

community Why does this industry still revolve around 5-AR inhibitors?

40 upvotes 5 years ago

Hair loss treatments still rely heavily on minoxidil, finasteride, and RU58841, with little innovation. Future treatments like stem cell therapy and RNA technology show promise but are not yet available.

community After quitting min and fin I asked AI on how fix the mess I am in and it says:

in Technology 1 year ago

Prolonged use of topical minoxidil and finasteride can lead to neuroendocrine and autonomic dysfunction, causing severe sensitivity and side effects. Recovery involves avoiding these treatments, supporting neurosteroid recovery, calming the sympathetic system, and rebuilding scalp health naturally.

community Oral minoxidil gives hair everywhere except scalp,plss help

in Minoxidil 41 upvotes 1 year ago

Oral minoxidil is causing body hair growth but not improving scalp hair, despite using dutasteride and finasteride. Users suggest waiting longer for results, checking vitamin levels, and considering additional treatments like topical minoxidil, dermarolling, and supplements.

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