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Research

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research Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABA_AReceptor Function and Seizure Susceptibility

269 citations , May 2002 in “Journal of Neuroscience”

This study observed that acute stress in rats increased neurosteroid levels linked to enhanced GABA(A) receptor function, raising seizure thresholds, while similar effects were seen in mice with deoxycorticosterone administration.

research Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABA_AReceptors

248 citations , December 2011 in “Journal of Neuroscience”

This study demonstrated that stress-derived neurosteroid THDOC shifts from inhibiting to activating the HPA axis under stress, presenting potential therapeutic targets for stress-related disorders.

research Neurosteroid Synthesis-Mediated Regulation of GABA_AReceptors: Relevance to the Ovarian Cycle and Stress

238 citations , February 2007 in “Journal of Neuroscience”

This study found that neurosteroids can reorganize GABA A receptors in mice, mimicking ovarian cycle changes, with the process being mediated by neurosteroid levels rather than direct hormone receptor activation.

research Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties

143 citations , May 2017 in “Nature cell biology”

This study found that the transcription factor Gata6 regulates the sebaceous duct lineage identity and plays a crucial role in epidermal wound healing by enabling dedifferentiation and broader lineage capabilities in post-mitotic cells.

research GABRA2 Alleles Moderate the Subjective Effects of Alcohol, Which are Attenuated by Finasteride

134 citations , February 2005 in “Neuropsychopharmacology”

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

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Community Join

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community Gaining or losing beard on fin

in Finasteride/Dutasteride 6 upvotes 8 months ago

Using finasteride may slow beard growth due to reduced DHT, but minoxidil can enhance beard growth. Some users report slower beard growth on finasteride, while others see continued improvement with minoxidil.

community Gaining back lost hair on fin (due to fin)?

in Finasteride/Dutasteride 6 upvotes 8 months ago

The conversation discusses hair loss treatment with finasteride, where the user is experiencing shedding and concerns about regrowth. Users advise patience, suggesting that visible improvement may take 6-12 months or longer, and recommend continuing the treatment.

community Galenic lotion. Science behind the components

in Treatment 1 upvotes 1 year ago

A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

community Gains or growth? Three months in

in Is this regrowth? 146 upvotes 1 year ago

The user is using topical minoxidil twice daily for hair regrowth and is hesitant to use finasteride due to concerns about hormonal effects. The conversation includes mixed opinions on the effectiveness of the treatment and suggestions to use a DHT blocker for better results.

community Gay men treat me as a completely different person since I moved to a buzz cut

273 upvotes 2 years ago

A gay man noticed a significant decrease in romantic interest after switching to a buzz cut, despite using minoxidil and finasteride for hair loss. Others in the conversation suggest that confidence and overall appearance matter more than hair, and recommend considering a hair system or focusing on fitness until a transplant is possible.

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Learn

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learn Gamma linolenic acid

learn Garlic

learn Ganiashi

learn Galanga root extract

learn Epigallocatechin gallate-glucoside

learn Scalp Micropigmentation

What guarantees do scalp micropigmentation providers offer? Most providers offer a 12-month guarantee for scalp micropigmentation.
What is Scalp Micropigmentation and how does it help people with visible hair loss? Scalp Micropigmentation creates the illusion of hair follicles on the scalp for visible hair loss.
Can scalp micropigmentation hide my scars? Scalp micropigmentation can significantly reduce the visibility of scars on the scalp.

learn Hair Transplant

Are hair transplant results guaranteed? Hair transplant results are not guaranteed and vary by individual.
When can I return to work after a hair transplant? Most patients can return to work within 2 to 7 days after a hair transplant.

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