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      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Ketoconazole

      antifungal with some anti-androgenic benefits, often used as a shampoo

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn GT20029

      research compound made to degrade androgen receptors in scalp

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

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      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Female AGA - Low Cortisol/Low DHEA

      in Female  6 upvotes 1 year ago
      Female (37) experiencing hair loss for 5 years, tried max dose of spiro and oral + topical minox without success. Discovered low cortisol and low DHEA levels, seeking functional medicine practitioner for help.

      community Sharing what worked for me (PCOS related hair loss)

      in Female  32 upvotes 10 months ago
      A user with PCOS experienced hair loss and found success using a triple dose of O.N.E Omega by Pure Encapsulations after discovering low Omega fatty acids. Biotin provided minimal improvement, but the Omega supplement significantly restored hair.