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GlossaryFollistatin (FST)

protein that inhibits activins, influencing muscle growth and hair

Follistatin, also known as FS or FST, is a protein that plays a crucial role in regulating various biological processes by binding to and inhibiting members of the TGF-beta superfamily, particularly activins. This inhibition is important for controlling muscle growth, inflammation, and tissue repair. In the context of hair biology, follistatin has been studied for its potential to promote hair growth and counteract conditions like alopecia by modulating the activity of growth factors involved in hair follicle development.

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research Identification of Key Genes and Signaling Pathways Related to Hetian Sheep Wool Density by RNA-Seq Technology

7 citations, May 2022 in “PLOS ONE”

Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.

research Impact of One-Week Administration of Dihydrotestosterone in Rat Anterior Pituitary Gland

1 citations, October 2022 in “International journal of endocrinology”

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

research Follistatin Promotes LIN28B-Mediated Supporting Cell Reprogramming and Hair Cell Regeneration in the Murine Cochlea

16 citations, February 2022 in “Science Advances”

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

research New Intranasal and Injectable Gene Therapy for Healthy Life Extension

June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

Gene therapy in mice increased lifespan and improved health without causing cancer.

research Telomere Dysfunction Impairs Epidermal Stem Cell Specification and Differentiation by Disrupting BMP/pSmad/P63 Signaling

19 citations, September 2019 in “PLOS genetics”

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

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community Why I really believe the tension theory is the cause of MPB

in Research/Science 70 upvotes 3 years ago

The conversation discusses the tension theory as a cause of male pattern baldness (MPB), suggesting that scalp tension and reduced subcutaneous fat layer contribute to hair loss. Treatments mentioned include Minoxidil, finasteride, microneedling, scalp massages, and Botox.