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research Frontal Fibrosing Alopecia: Successfully Treated with Methotrexate or Just the Natural Disease Progression?

4 citations , December 2020

This case report describes a woman with frontal fibrosing alopecia who did not improve with hydroxychloroquine and topical minoxidil but achieved clinical stabilization with methotrexate monotherapy.

research Guidelines for clinical trials of frontal fibrosing alopecia: consensus recommendations from the International FFA Cooperative Group (IFFACG)*

14 citations , June 2021 in “British journal of dermatology/British journal of dermatology, Supplement”

This paper presents consensus guidelines for standardized diagnostic criteria and assessment methods for frontal fibrosing alopecia to improve clinical research and data collection globally.

research A review of Janus kinase inhibitor use in scarring alopecia

4 citations , January 2025 in “JAAD reviews.”

This review discusses how JAK inhibitors, like tofacitinib and baricitinib, show promise in improving conditions like lichen planopilaris and frontal fibrosing alopecia by reducing severity scores and enhancing hair regrowth, though further research on safety and personalized approaches is needed.

research Refractory alopecia areata with single hairs imitating frontal fibrosing alopecia: a prospective observational study

2 citations , December 2023 in “International Journal of Dermatology”

In this study, researchers identified a unique variant of alopecia areata characterized by an increase in telogen hair follicles and minimal inflammation present in the microenvironment.

research Frontal Fibrosing Alopecia: An Update on Pathogenesis, Diagnosis, and Treatment

61 citations , January 2019 in “American Journal of Clinical Dermatology”

This review discusses the potential causes and treatments for frontal fibrosing alopecia but reports no new clinical findings, highlighting the need for further research to understand its pathogenesis and develop validated treatments.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Finasteride not working isnt it MPB?

in Finasteride/Dutasteride 6 upvotes 2 years ago

A user is concerned that finasteride isn't working for their hair loss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.

community 18M Experiencing Hair Loss Since 15: Seeking Alternatives to Minoxidil

in General 290 upvotes 8 months ago

An 18-year-old experiencing balding since age 15 is seeking alternatives to minoxidil for hair regrowth, currently using rosemary oil and a 0.5mm derma roller. They are unsure about the proper use of these treatments.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

41 upvotes 1 year ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community Occipitalis Muscle Tension Theory

13 upvotes 7 months ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

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Learn

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learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

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Hair Systems
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