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insertion or deletion of nucleotides shifts DNA reading frame

A frameshift mutation is a type of genetic mutation where the insertion or deletion of a number of nucleotides in DNA that is not divisible by three shifts the reading frame of the genetic code. This alteration can lead to the production of completely different proteins, often resulting in nonfunctional proteins, which can cause various genetic disorders and diseases.

Related Terms

• Point Mutation
• Insertion Mutation
• Deletion Mutation
• Genetic Mutation
• Nonsense Mutation
• Genetic Mutation
• Missense Mutation