October 2024 in “Zagazig University Medical Journal” This clinical trial found that transdermal delivery of 5-Fluorouracil using fractional CO2 laser resulted in a significantly better treatment response in alopecia areata patients compared to intralesional injections of the same drug, with a greater reduction in the Severity of Alopecia Tool Score.
April 2024 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study at Al-Azhar University Hospitals found that combining a fractional CO2 laser or microneedling with topical 5-Fluorouracil (5-FU) is more effective and safe for treating vitiligo than using either treatment alone, offering a new therapeutic option for patients.
April 2024 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” In this study, vitiligo patients treated with a combination of fractional CO2 laser or microneedling followed by topical 5-Fluorouracil experienced more effective and safe outcomes compared to using either method alone.
2 citations
,
April 2025 in “Lasers in Medical Science” This study found that combining fractional CO₂ laser with halometasone cream improved chronic eczema more effectively than halometasone alone, with efficacy varying by laser parameters and showing better results at 4 weeks compared to 1 week. Pain was noted with higher energy treatments.
April 2023 in “Research Square (Research Square)” The researchers reported that combining stromal vascular fraction (SVF) with fractional CO2 laser treatment significantly improved burn scar outcomes and patient satisfaction compared to using the laser alone.